Status: Non-profit private foundation established on 1894

Mission: basic and applied biomedical research with emphasis on all aspects of public health

Largest scientific campus North of Paris:
- 1300 workers at 15 research units
- a teaching service
- a health expertise network
- a health service
- diverse technological platforms

Participation of IPL in TB PAN-NET

WP1: "Molecular epidemiology of drug resistant strains  in selected metropolitan settings in Western and Eastern Europe "

1. molecular characterization of the MDR-TB and sensitive strains collected in Paris
2. identification of clinical and social risk factors associated with the development of drug resistant TB
3. integration of the molecular data and the epidemiological information to define TB transmission patterns by identifying both unsuspected risk factors and transmission networks.
   

Scientific team. From left to right

Eve Willery, Caroline Allix, Guy Delcroix, Cristina Gutierrez, Philip Supply

 

 

 

 

 

 

Relevant publications

Allix-Béguec C, Supply P, Wanlin M, Bifani P, Fauville-Dufaux M (2008) Standardised PCR-based molecular epidemiology of tuberculosis. Eur Respir J 31:1077-84.

Gutierrez MC, Ahmed N, Willery E, Narayanan S, Hasnain SE, Chauhan DS, Katoch VM, Vincent V, Locht C, Supply P (2006) Predominance of ancestral lineages of M. tuberculosis in India denotes an ancient focus of tuberculosis in South Asia. Emerg Infect Dis 12: 1367-74.

Supply, P, Allix C, Lesjean S, Cardoso M, Willery E, Savine E, de Haas P, van Deutekom H, Roring S, Bifani P, Kreiswirth B, Sola C, Rastogi N, Vatin V, Gutierrez MC et als (2006). Proposal for standardization of optimized Mycobacterial Interspersed Repetitive Unit-Variable Number Tandem Repeat typing of M. tuberculosis. J Clin Microbiol 44: 4498-510.

Kremer K, Ahmed N, Arnold C, Cataldi A, Gutierrez MC et als (2005) Discriminatory power and reproducibility of novel DNA typing methods for M. tuberculosis complex strains. J Clin Microbiol 43: 5628-38.

Gutierrez MC, Vincent V (2002) Contribution du typage moléculaire à la surveillance de la tuberculose multirésistante en France, 1995-2000. Bul Epidemiol Hebdomadaire 16-17/2002: 73-5.

Hanau-Bercot B, Gremy I, Raskine L, Gutierrez MC et als (2000) A one-year prospective study (1994-1995) for a first evaluation of tuberculosis transmission in French prisons. Int J Tuberc Lung Dis 4: 853-9.

Gutierrez MC et als (1998) Molecular fingerprinting of M. tuberculosis and risk factors for recently transmitted tuberculosis in Paris and surrounding area. J Clin Microbiol 36: 486-92.